The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 27, 2022
Filed:
Sep. 28, 2020
Applicant:
Johnson Matthey Public Limited Company, London, GB;
Inventor:
Padmini Kavuru, Devens, MA (US);
Assignee:
Macfarlan Smith Limited, Edinburgh, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 19/19 (2006.01);
U.S. Cl.
CPC ...
C07H 19/19 (2013.01); C07B 2200/13 (2013.01);
Abstract
The invention relates to a crystalline methanol or dimethyl sulfoxide solvated form of regadenoson and an anhydrous polymorph of regadenoson. The invention is also directed to the preparation of the methanol or dimethyl sulfoxide solvated and anhydrous solid-state forms of regadenoson. In particular, the invention relates to the preparation of the anhydrous polymorph of regadenoson in a stable form from the dimethyl sulfoxide solvated form of regadenoson, which preparation is purifiable and scalable.