The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 27, 2022

Filed:

May. 20, 2021
Applicant:

Hanmi Pharmaceutical Co., Ltd., Hwaseong-si, KR;

Inventors:

Seung Hyun Jung, Hwaseong-si, KR;

Dong Jin Hong, Hwaseong-si, KR;

Ji Young Hwang, Hwaseong-si, KR;

Seo Hee Kim, Hwaseong-si, KR;

So Min Park, Hwaseong-si, KR;

Shin Mee Mah, Hwaseong-si, KR;

Young Gil Ahn, Hwaseong-si, KR;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 491/056 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07D 491/056 (2013.01); A61P 35/00 (2018.01);
Abstract

Disclosed are novel dioxoisoquinolinone derivative compounds, pharmaceutically acceptable salts thereof, optical isomers, hydrates, and solvates thereof as well as uses thereof. More specifically, the novel dioxoisoquinolinone derivative compounds, pharmaceutically acceptable salts, optical isomers, hydrates, solvates show inhibition activity of EZH1 (Enhancer of zeste homolog 1) and/or EZH2 (Enhancer of zeste homolog 2) activity. Pharmaceutical compositions containing the compound is also disclosed.


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