The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 27, 2022
Filed:
Apr. 16, 2019
Applicant:
Chinoin Gyógyszer És Vegyészeti Termékek Gyára Zrt., Budapest, HU;
Inventors:
Imre Rozsumberszki, Budapest, HU;
Zsuzsanna Kardos, Budapest, HU;
Irén Hortobágyi, Budapest, HU;
Tibor Szabó, Budapest, HU;
Csaba Váradi, Budapest, HU;
Tamás Bán, Budapest, HU;
Assignee:
CHINOIN GYÓGYSZER ÉS VEGYÉSZETI TERMÉKEK GYÁRA ZRT., Budapest, HU;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07C 51/09 (2006.01); C07C 67/31 (2006.01); C07C 59/46 (2006.01); C07C 69/608 (2006.01);
U.S. Cl.
CPC ...
C07C 51/09 (2013.01); C07C 67/31 (2013.01); C07B 2200/13 (2013.01); C07C 59/46 (2013.01); C07C 69/608 (2013.01); C07C 2602/22 (2017.05);
Abstract
The present invention relates to a process for the preparation of iloprost of formula I through new intermediates, isolation of iloprost of formula I in solid form, as well as preparation of the 16(S)-iloprost and 16(R)-iloprost isomers of formulae (S)-I and (R)-I and isolation of iloprost of formula I and 16(S)-iloprost of formula (S)-I in solid, crystalline form.