The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 27, 2022
Filed:
Dec. 06, 2016
Compositions and methods relating to t peripheral helper cells in autoantibody-associated conditions
Applicant:
The Brigham and Women's Hospital, Inc., Boston, MA (US);
Inventors:
Michael B. Brenner, Newton, MA (US);
Deepak A. Rao, Jamaica Plain, MA (US);
Assignee:
The Brigham and Women's Hospital, Inc., Boston, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/68 (2017.01); A61P 19/02 (2006.01); A61K 39/395 (2006.01); A61K 45/06 (2006.01); A61K 51/10 (2006.01); A61K 51/12 (2006.01); C07K 16/28 (2006.01); C07K 16/46 (2006.01); C12N 5/0783 (2010.01); G01N 33/564 (2006.01); G01N 33/569 (2006.01);
U.S. Cl.
CPC ...
A61K 47/6849 (2017.08); A61K 39/3955 (2013.01); A61K 45/06 (2013.01); A61K 51/1027 (2013.01); A61K 51/1033 (2013.01); A61K 51/1203 (2013.01); A61P 19/02 (2018.01); C07K 16/2818 (2013.01); C07K 16/2833 (2013.01); C07K 16/2866 (2013.01); C07K 16/468 (2013.01); C12N 5/0636 (2013.01); G01N 33/564 (2013.01); G01N 33/56972 (2013.01); C07K 2317/31 (2013.01); C07K 2319/00 (2013.01); G01N 2333/70539 (2013.01); G01N 2333/70596 (2013.01); G01N 2333/7158 (2013.01); G01N 2800/102 (2013.01);
Abstract
This disclosure provides methods and compositions for detecting Tph cells and/or reducing the number (or frequency) and/or activity of such cells in order to provide therapeutic benefit to a subject having or at risk of developing an autoantibody-associated condition such as an autoantibody-associated autoimmune disease.