The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 27, 2022
Filed:
May. 11, 2016
Applicant:
University Health Network, Toronto, CA;
Inventors:
Li Zhang, Toronto, CA;
Paulina Achita, Mississauga, CA;
Jong Lee, Toronto, CA;
Dalam Ly, Toronto, CA;
Dzana Dervovic, Toronto, CA;
Assignee:
University Health Network, Toronto, CA;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/17 (2015.01); C12N 5/0783 (2010.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 35/17 (2013.01); A61P 35/00 (2018.01); C12N 5/0637 (2013.01); C12N 2501/51 (2013.01); C12N 2501/515 (2013.01); C12N 2501/999 (2013.01);
Abstract
There is provided herein a method for expanding human CD4-CD8- regulatory T cells (DN Tregs) from a population of cells comprising DN Tregs, comprising: culturing the population of cells with artificial antigen presenting cells (APCs), preferably the DN Tregs are αβ-TCR-CD56- or alternatively γ8-TCR+.