The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 27, 2022

Filed:

Nov. 16, 2020
Applicant:

Karuna Therapeutics, Inc., Boston, MA (US);

Inventors:

James A. Monn, Indianapolis, IN (US);

Clifford Adam Schlecht, St. Louis, MO (US);

Dennis A. Bennett, Rio Grande, PR (US);

Giorgio Attardo, Boston, MA (US);

Assignee:

Karuna Therapeutics, Inc., Boston, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 417/04 (2006.01); A61K 31/4439 (2006.01); A61K 31/46 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4439 (2013.01); A61K 31/46 (2013.01); C07D 417/04 (2013.01);
Abstract

Provided herein are compounds comprising compounds of formula I and/or salts thereof;wherein at least one of R, R, R, R, R, R, R, R, R, R, R, R, and Ris fluorine, and the remainder are independently chosen from hydrogen and fluorine; and R, R, R, R, R, R, R, R, R, and Rare independently chosen from hydrogen and deuterium; with the proviso that when R, R, and Rare fluorine, then at least one of R, R, R, R, R, R, R, R, R, and Ris fluorine or at least one of R, R, R, R, R, R, R, R, R, and Ris deuterium. Also provided are medicaments comprising these compounds and methods for treating central nervous system disorders with the compounds and medicaments described herein.


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