The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 20, 2022

Filed:

Jan. 12, 2017
Applicants:

Advanced Polymer Monitoring Technologies, Inc., New Orleans, LA (US);

The Administrators of the Tulane Education Fund, New Orleans, LA (US);

Inventors:

Wayne Frederick Reed, New Orleans, LA (US);

Daniel J. Rees, New Orleans, LA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G16C 20/20 (2019.01); G01N 15/00 (2006.01);
U.S. Cl.
CPC ...
G16C 20/20 (2019.02); G01N 2015/0038 (2013.01); G01N 2015/0053 (2013.01); G01N 2015/0092 (2013.01);
Abstract

Method, device, and system for identifying a model-based time dependent light scattering signature that includes receiving an experimental time dependent light scattering signature comprising experimental data descriptive of an average molecular weight of protein components in a solution over time. The method further includes identifying an Ansatz for evaluating the experimental time dependent light scattering signature, the Ansatz being an initial model-based time dependent light scattering signature, the initial model-based time dependent light scattering signature identifying at least one key variable. The method also includes adjusting the at least one key variable in the initial model-based time dependent light scattering signature until a final model-based time dependent light scattering signature is identified. In some instances, the final model-based time dependent light scattering signature identifies at least one protein aggregation mechanism.


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