The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 20, 2022

Filed:

Oct. 24, 2018
Applicant:

Korea Basic Science Institute, Daejeon, KR;

Inventors:

Gun H. Kim, Daejeon, KR;

Edmond C. Park, Sejong-Si, KR;

Seung I. Kim, Daejeon, KR;

Sang-Yeop Lee, Daejeon, KR;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2018.01); G01N 33/50 (2006.01); G01N 33/53 (2006.01); A61K 31/7088 (2006.01); C07K 16/18 (2006.01); G16H 50/20 (2018.01); G16B 20/00 (2019.01); G16B 40/00 (2019.01);
U.S. Cl.
CPC ...
G01N 33/5023 (2013.01); A61K 31/7088 (2013.01); C07K 16/18 (2013.01); G01N 33/5308 (2013.01); G16B 20/00 (2019.02); G16B 40/00 (2019.02); G16H 50/20 (2018.01); G01N 2500/10 (2013.01); G01N 2800/34 (2013.01); G01N 2800/60 (2013.01);
Abstract

The present invention relates to a biomarker for diagnosis of overactive bladder (OAB) disease, and a method for screening a drug using the biomarker. The markers described in the present invention can effectively detect or diagnose the onset of OAB by distinguishing them from normal populations. In particular, OAB-specific protein markers released into urine enable simple and rapid OAB diagnosis in a non-invasive manner. In addition, by selecting an agent that changes, particularly normalizes the expression and activity of the markers selected in the present invention, more effective preventative or therapeutic agents of OAB disease can be screened.


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