The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 20, 2022
Filed:
Jul. 19, 2017
The Johns Hopkins University, Baltimore, MD (US);
The Trustees of the University of Pennsylvania, Philadelphia, PA (US);
Sharon Gerecht, Severna Park, MD (US);
Daniel Lewis, Riverside, CT (US);
Kyung Min Park, Baltimore, MD (US);
T. S. Karin Eisinger, Philadelphia, PA (US);
M. Celeste Simon, Philadelphia, PA (US);
The Johns Hopkins University, Baltimore, MD (US);
The Trustees of the University of Pennsylvania, Philadelphia, PA (US);
Abstract
The present invention describes methods for quantifying and analyzing cell migration and drug screening. Such methods include a gel (or a hydrogel) comprising a polymer, and cells that forms an oxygen gradient within the gel by controlling the balance of the diffusion of oxygen through the top of the gel and by the consumption of oxygen uptake by the cells. The migration of the cells is determined while the cells are grown in the gel of the present invention.