The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 20, 2022

Filed:

Jun. 11, 2018
Applicant:

Translate Bio, Inc., Lexington, MA (US);

Inventors:

Frank DeRosa, Lexington, MA (US);

Michael Heartlein, Lexington, MA (US);

Shrirang Karve, Lexington, MA (US);

Yi Zhang, Lexington, MA (US);

Assignee:

Translate Bio, Inc., Lexington, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C08G 79/04 (2006.01); A61K 38/53 (2006.01); A61K 47/34 (2017.01); C08F 293/00 (2006.01); A61K 31/7088 (2006.01);
U.S. Cl.
CPC ...
C08G 79/04 (2013.01); A61K 38/53 (2013.01); A61K 47/34 (2013.01); C08F 293/00 (2013.01); A61K 31/7088 (2013.01);
Abstract

Disclosed are polymers comprising the moiety A, which is a moiety of formula I: and pharmaceutically acceptable salts thereof, wherein R, R, R, L, n1 and n2 are as defined herein. These polymers are useful for delivering nucleic acids to subject. These polymers and pharmaceutically acceptable compositions comprising such polymers and nucleic acids can be useful for treating various diseases, disorders and conditions.


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