The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 20, 2022

Filed:

Dec. 27, 2017
Applicant:

Shenzhen Beike Biotechnology Co., Ltd, Shenzhen, CN;

Inventors:

Fengyu Zhang, Tianjin, CN;

Bin Gao, Tianjin, CN;

Lei Wang, Tianjin, CN;

Yasong Wu, Tianjin, CN;

Qing Wei, Tianjin, CN;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); C07K 14/54 (2006.01); C07K 14/705 (2006.01); C07K 14/715 (2006.01); C07K 16/46 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2803 (2013.01); C07K 14/5443 (2013.01); C07K 14/70521 (2013.01); C07K 14/70532 (2013.01); C07K 14/7155 (2013.01); C07K 16/2809 (2013.01); C07K 16/2833 (2013.01); C07K 16/468 (2013.01); C07K 2317/31 (2013.01); C07K 2317/569 (2013.01); C07K 2317/622 (2013.01); C07K 2319/02 (2013.01); C07K 2319/30 (2013.01);
Abstract

A multifunctional polypeptide chain or a protein. A polypeptide chain X, comprising an antigen 1 binding domain R1, an auxiliary peptide chain linking domain R2 and an antigen 2 binding domain R3. The auxiliary peptide chain linking domain R2 is a cytokine or a cytokine binding domain in a cytokine receptor. A protein, which is a heterodimer composed of the polypeptide chain X as a main peptide chain and an auxiliary peptide chain Y. The auxiliary peptide chain Y comprises an antigen 3 binding domain R4 and a main peptide chain X linking domain R5, or the auxiliary peptide chain Y is the main peptide chain linking domain R5. The multifunctional protein mediates specific cell killing by binding to different tumor antigens with the two antigen binding domains of tumor-associated antigens therein. The multifunctional protein can function as a cytokine by introducing a cytokine or a cytokine receptor complex.


Find Patent Forward Citations

Zhang, Fengyu. (2022). Multifunctional protein (U.S. Patent No. 11530264). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11530264

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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