The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 20, 2022
Filed:
May. 15, 2020
Applicant:
Trustees of Boston University, Boston, MA (US);
Inventors:
Ahmad S. Khalil, Lexington, MA (US);
Wilson Wai Chun Wong, Brookline, MA (US);
Divya Israni, Boston, MA (US);
Huishan Li, Brookline, MA (US);
Assignee:
TRUSTEES OF BOSTON UNIVERSITY, Boston, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/47 (2006.01);
U.S. Cl.
CPC ...
C07K 14/4702 (2013.01); C07K 2319/09 (2013.01); C07K 2319/20 (2013.01); C07K 2319/50 (2013.01); C07K 2319/715 (2013.01); C07K 2319/81 (2013.01);
Abstract
The technology described herein is directed to regulated synthetic gene expression systems. In one aspect described herein are synthetic transcription factors (synTFs) comprising a DNA binding domain, a transcriptional effector domain, and a regulator protein. In other aspects described herein are gene expression systems comprising said synTFs and methods of treating diseases and disorders using said synTFs.