The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 20, 2022
Filed:
Dec. 16, 2019
Applicant:
Oregon Health & Science University, Portland, OR (US);
Inventors:
Michael Cohen, Portland, OR (US);
Ian Carter-O'Connell, Portland, OR (US);
Rory Morgan, Portland, OR (US);
Haihong Jin, Portland, OR (US);
Assignee:
Oregon Health & Science University, Portland, OR (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07H 19/207 (2006.01); C12N 9/10 (2006.01); C12Q 1/48 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07H 19/207 (2013.01); C12N 9/1077 (2013.01); C12Q 1/48 (2013.01); C12Y 204/0203 (2013.01); G01N 2333/91142 (2013.01); G01N 2500/02 (2013.01); G01N 2500/10 (2013.01);
Abstract
Mutant mono ADP-ribose-polymerases (mono-PARP) proteins and small molecule compound substrates specific for the mutant mono-PARP proteins as well as methods of using these compositions to identify protein targets of the mono-PARPs and to screen for antagonists of the mono-PARPs are described.