The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 20, 2022
Filed:
Jan. 20, 2021
Applicant:
Incyte Corporation, Wilmington, DE (US);
Inventors:
Le Zhao, Wilmington, DE (US);
Xiaozhao Wang, Mt. Laurel, NJ (US);
Wenyu Zhu, Wilmington, DE (US);
Haolin Yin, Wilmington, DE (US);
Liangxing Wu, Wilmington, DE (US);
Wenqing Yao, Wilmington, DE (US);
Assignee:
INCYTE CORPORATION, Wilmington, DE (US);
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/20 (2006.01); C07D 471/22 (2006.01); C07D 491/20 (2006.01); C07D 498/20 (2006.01);
U.S. Cl.
CPC ...
C07D 471/20 (2013.01); C07D 471/22 (2013.01); C07D 491/20 (2013.01); C07D 498/20 (2013.01);
Abstract
Disclosed are spirocyclic compounds of Formula I, methods of using the compounds for inhibiting KRAS activity and treating cancer, and pharmaceutical compositions comprising such compounds. The compounds are useful in treating, preventing or ameliorating diseases or disorders associated with KRAS activity such as cancer.