The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 20, 2022
Filed:
Feb. 23, 2022
Applicant:
Insilico Medicine Ip Limited, Hong Kong, HK;
Inventors:
Aleksandrs Zavoronkovs, Pak Shek Kok, HK;
Aleksandr Aliper, Ramenskoye, RU;
Vladimir Aladinskiy, Kaliningrad, RU;
Andrey Kukharenko, Moscow, RU;
Assignee:
Insilico Medicine IP Limited, Hong Kong, HK;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/06 (2006.01); C07D 403/14 (2006.01); C07D 233/90 (2006.01); C07D 401/04 (2006.01); A61P 11/00 (2006.01); C07D 405/04 (2006.01); A61P 13/12 (2006.01); C07D 487/08 (2006.01);
U.S. Cl.
CPC ...
C07D 403/14 (2013.01); A61P 11/00 (2018.01); A61P 13/12 (2018.01); C07D 233/90 (2013.01); C07D 401/04 (2013.01); C07D 405/04 (2013.01); C07D 487/08 (2013.01);
Abstract
The disclosure provides TNIK and/or MAP4K4 kinases inhibitors for the treatment of disease. In one aspect, disclosed herein are kinase inhibitors having a structure of Formula (A), (A*), (I), (IIA), or (IIB). Further described herein are pharmaceutical composition comprising these compounds and methods of using these compounds. In one aspect, disclosed herein are methods of treating a disease or condition by administering the kinases inhibitors described herein.