The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 20, 2022

Filed:

Sep. 16, 2013
Applicant:

W. R. Grace & Co.-conn., Columbia, MD (US);

Inventor:

Feng Gu, Ellicott City, MD (US);

Assignee:

W.R. GRACE & CO.-CONN., Columbia, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01J 20/283 (2006.01); B01J 20/24 (2006.01); B01J 20/02 (2006.01); B01J 20/04 (2006.01); B01J 20/26 (2006.01); B01D 15/36 (2006.01); B65B 3/04 (2006.01); B65B 7/02 (2006.01); C08F 222/38 (2006.01); G01N 30/88 (2006.01); G01N 30/96 (2006.01);
U.S. Cl.
CPC ...
B01J 20/283 (2013.01); B01D 15/361 (2013.01); B01J 20/0229 (2013.01); B01J 20/0248 (2013.01); B01J 20/04 (2013.01); B01J 20/24 (2013.01); B01J 20/261 (2013.01); B01J 20/262 (2013.01); B01J 20/264 (2013.01); B65B 3/04 (2013.01); B65B 7/02 (2013.01); C08F 222/38 (2013.01); B01J 2220/44 (2013.01); B01J 2220/46 (2013.01); B01J 2220/52 (2013.01); B01J 2220/58 (2013.01); B01J 2220/62 (2013.01); G01N 30/96 (2013.01); G01N 2030/8813 (2013.01); Y10T 428/2982 (2015.01);
Abstract

Functionalized particulate support material and chromatographic media prepared therefrom are disclosed. The functionalized particulate support material is a plurality of particles, each particle having a particle surface. Chemically bonded to and extending from the surface of the particles is a combination of hydrophobic and hydrophilic functional groups. The hydrophobic functional groups enable polymerization of one or more monomers onto the particle surface while the hydrophilic functional groups provide increased wettability of the particle surface compared to an unmodified particle surface. The functionalized particulate support material may be further processed so as to form polymer chains extending from the hydrophobic functional groups. In one embodiment, the resulting polymer functionalized material is useful as a chromatographic media in chromatography columns or cartridges, such as in a liquid chromatography (HPLC) column. Chromatography columns or cartridges containing the polymer functionalized media, and methods of making and using the media, are also disclosed.


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