The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 20, 2022

Filed:

Dec. 27, 2016
Applicant:

Cognos Therapeutics Inc., Los Angeles, CA (US);

Inventors:

Roger Kornberg, Atherton, CA (US);

Yehoshua Shachar, Santa Monica, CA (US);

Thomas Chen, La Canada Flintridge, CA (US);

Assignee:

Cognos Therapeutics Inc., Inglewood, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61M 27/00 (2006.01); A61M 1/16 (2006.01); A61M 1/14 (2006.01); C07K 16/18 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
A61M 1/16 (2013.01); A61M 1/14 (2013.01); C07K 16/18 (2013.01); G01N 33/6896 (2013.01); A61M 27/006 (2013.01); A61M 2202/0464 (2013.01); A61M 2210/0693 (2013.01); C07K 2317/24 (2013.01); G01N 2333/4709 (2013.01); G01N 2800/2821 (2013.01); G01N 2800/2835 (2013.01); G01N 2800/52 (2013.01);
Abstract

An apparatus for performing cerebral micro-dialysis to treat neurological disease of a patient's brain includes a catheter for implantation in or near the patient's brain, an implantable pump communicated with the catheter to transport cerebrospinal fluid (CSF) from the patient, which CSF contains diseased cells or biomolecules associated with the neurological disease, and an implantable separation device communicated with the pump wherein the diseased cells or biomolecules are removed, where the separation apparatus includes a dialysis membrane impregnated with an antibody, a reversible electrostatic filter, and/or a magnetic field effect fractionation chamber wherein a magnetically-tagged antibody scavenges and aids in the removal of circulating diseased cells or biomolecules from the CSF.


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