The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 20, 2022

Filed:

Nov. 05, 2015
Applicants:

Organovo, Inc., San Diego, CA (US);

L'oreal, Paris, FR;

Inventors:

Kelsey Nicole Retting, San Diego, CA (US);

Colin M. O'Neill, La Jolla, CA (US);

Deborah Lynn Greene Nguyen, San Diego, CA (US);

Sharon C. Presnell, Poway, CA (US);

Jessica Langer, Teaneck, NJ (US);

Guive Balooch, New York, NY (US);

Elizabeth Wu, San Francisco, CA (US);

Julien Demaude, Paris, FR;

Assignees:

Organovo, Inc., San Diego, CA (US);

L'Oreal, Paris, FR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61L 27/60 (2006.01); A61L 27/36 (2006.01); C12N 5/071 (2010.01); A61L 27/50 (2006.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
A61L 27/362 (2013.01); A61L 27/50 (2013.01); A61L 27/60 (2013.01); C12N 5/0698 (2013.01); G01N 33/5044 (2013.01); A61L 2300/64 (2013.01); C12N 2502/091 (2013.01); C12N 2502/094 (2013.01); C12N 2502/1323 (2013.01); C12N 2503/06 (2013.01); C12N 2533/54 (2013.01); C12N 2533/74 (2013.01); C12N 2533/90 (2013.01); C12N 2535/00 (2013.01);
Abstract

Disclosed are bioprinted, three-dimensional, biological skin tissues comprising: a dermal layer comprising dermal fibroblasts; and an epidermal layer comprising keratinocytes, the epidermal layer in contact with the dermal layer to form the three-dimensional, engineered, biological skin tissue. Also disclosed are arrays of engineered skin tissues and methods of making engineered skin tissues.


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