The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 20, 2022
Filed:
Jun. 10, 2021
Applicant:
Prokarium Limited, London, GB;
Inventors:
Livija Deban, London, GB;
Hyam Levitsky, Seattle, WA (US);
Assignee:
PROKARIUM LIMITED, London, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 63/00 (2020.01); A61K 35/74 (2015.01); A61P 35/00 (2006.01); A61K 45/06 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 35/74 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01); A61K 9/0053 (2013.01);
Abstract
The present invention relates to the field of cancer therapy. In particular, the present invention relates to a live attenuated Gram-negative bacterium for use in the treatment, reduction, inhibition or control of a neoplastic disease in a subject undergoing or intended to undergo immunotherapy with a checkpoint inhibitor therapy, an adoptive T cell therapy and/or an allogeneic or an autologous CAR-T therapy simultaneously, separately or sequentially with the administration of the live attenuated Gram-negative bacterium.