The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 20, 2022

Filed:

Aug. 21, 2020
Applicant:

Bayer Pharma Aktiengesellschaft, Berlin, DE;

Inventors:

Lars Wortmann, Berlin, DE;

Ulrich Lücking, Berlin, DE;

Julien Lefranc, Berlin, DE;

Hans Briem, Berlin, DE;

Marcus Koppitz, Berlin, DE;

Knut Eis, Berlin, DE;

Franz Von Nussbaum, Lyons, FR;

Benjamin Bader, Berlin, DE;

Antje Margret Wengner, Berlin, DE;

Gerhard Siemeister, Berlin, DE;

Wilhelm Bone, Berlin, DE;

Philip Lienau, Berlin, DE;

Joanna Grudzinska-Goebel, Berlin, DE;

Dieter Moosmayer, Berlin, DE;

Uwe Eberspächer, Berlin, DE;

Hans Schick, Berlin, DE;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/4375 (2006.01); A61K 31/5377 (2006.01); A61K 31/4155 (2006.01); C07D 471/04 (2006.01); C07D 519/00 (2006.01); C07D 413/14 (2006.01); A61P 35/00 (2006.01); A61P 35/02 (2006.01); A61K 31/541 (2006.01); A61K 31/5386 (2006.01); A61K 31/55 (2006.01); A61K 31/675 (2006.01); A61K 45/06 (2006.01); C07D 491/22 (2006.01); C07F 9/6561 (2006.01);
U.S. Cl.
CPC ...
A61K 31/541 (2013.01); A61K 31/5377 (2013.01); A61K 31/5386 (2013.01); A61K 31/55 (2013.01); A61K 31/675 (2013.01); A61K 45/06 (2013.01); C07D 471/04 (2013.01); C07D 491/22 (2013.01); C07D 519/00 (2013.01); C07F 9/6561 (2013.01);
Abstract

The present invention relates to substituted 2-(morpholin-4-yl)-1,7-naphthyridine compounds of general formula (I) or (Ib), to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyperproliferative disease as a sole agent or in combination with other active ingredients.


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