The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 20, 2022

Filed:

Jun. 18, 2018
Applicants:

University of Pittsburgh—of the Commonwealth System of Higher Education, Pittsburgh, PA (US);

Department of Veterans Affairs, Washington, DC (US);

Inventors:

Kia M. Washington, Pittsburgh, PA (US);

William R. Wagner, Gibsonia, PA (US);

Michael Brandt Steketee, Wexford, PA (US);

Yolandi Van der Merwe, Pittsburgh, PA (US);

Xinzhu Gu, Jefferson Hills, PA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/70 (2006.01); A61P 25/00 (2006.01); A61K 47/34 (2017.01); A61K 31/436 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 9/7007 (2013.01); A61K 9/0024 (2013.01); A61K 31/436 (2013.01); A61K 47/34 (2013.01); A61P 25/00 (2018.01);
Abstract

Devices for local delivery of tacrolimus or a derivative thereof are provided, wherein the devices comprise a polymeric matrix containing tacrolimus or a derivative thereof that provides for delayed and extended release of tacrolimus or a derivative thereof. The devices can locally deliver tacrolimus or a derivative thereof to injured nervous system tissue upon implantation in a subject. Thus, techniques for local delivery of tacrolimus or a derivative thereof and methods of treatment using such devices are also provided.


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