The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 20, 2022
Filed:
Jul. 22, 2020
R.p. Scherer Technologies, Llc, Carson City, NV (US);
University of Mississippi, University, MS (US);
Sampada Bhaskar Upadhye, Princeton, NJ (US);
Ronald S. Vladyka, Somerset, NJ (US);
Michael Andrew Repka, Oxford, MS (US);
Jun-Bom Park, Seoul, KR;
Roshan Vijay Tiwari, Hillsborough, NJ (US);
Hemlata Gunga Patil, Hillsborough, NJ (US);
Joseph Thomas Morott, Jr., Morgantown, WV (US);
Wenli Lu, Shanghai, CN;
R.P. Scherer Technologies, LLC, Carson City, NV (US);
UNIVERSITY OF MISSISSIPPI, University, MS (US);
Abstract
A dry granulation process using a twin-screw extruder for granulating a powder mixture which includes at least one active ingredient and at least one carrier. The process includes steps of kneading the powder mixture in the screw barrel of the twin-screw extruder at a barrel temperature below a melting point of the at least one active ingredient and a melting point or a glass transition temperature of the at least one carrier to provide a kneaded powder mixture, and extruding the kneaded powder mixture to form granules. Granules and tablets produced using the dry granulation process in the twin-screw extruder are also provided.