The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 20, 2022

Filed:

Apr. 29, 2021
Applicants:

University of Washington, Seattle, WA (US);

Seattle Children's Hospital, Seattle, WA (US);

Inventors:

James Chen, Seattle, WA (US);

Tanner Clark, Seattle, WA (US);

Thomas Lendvay, Seattle, WA (US);

Assignees:

UNIVERSITY OF WASHINGTON, Seattle, WA (US);

Seattle Children's Hospital, Seattle, WA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B 17/20 (2006.01); A61M 5/31 (2006.01); A61M 5/32 (2006.01); A61K 9/00 (2006.01); A61K 39/215 (2006.01); B01L 3/02 (2006.01); A61K 41/00 (2020.01); A61B 10/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61B 17/20 (2013.01); A61K 9/0021 (2013.01); A61K 39/215 (2013.01); A61K 41/0057 (2013.01); A61M 5/3145 (2013.01); A61M 5/3293 (2013.01); B01L 3/02 (2013.01); A61B 10/0045 (2013.01); A61K 2039/54 (2013.01); A61M 2202/30 (2013.01); A61M 2205/7509 (2013.01); A61M 2209/04 (2013.01); B01L 2300/0681 (2013.01);
Abstract

An apparatus for vaccine generation includes a syringe with a cavity that includes a solution with photosensitizers. Microbial particles are added to the solution. A light source is capable of emitting one or more wavebands of light that are effectively absorbed by the one photosensitizers to generate singlet oxygen in the solution and other radical species that rapidly react with and damage lipids, proteins, DNA, and RNA of the microbial particles. This damage produces immunogens that can be applied as a vaccine to viruses and other infectious microbial particles. A plunger that fits within a proximal opening in the syringe is used for forcing the solution including the immunogens through the filter and out of the syringe while the photosensitizers, debris and unwanted microbial particles are trapped within the filter.


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