The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 20, 2022
Filed:
Jul. 14, 2015
Regeneron Pharmaceuticals, Inc., Tarrytown, NY (US);
Lynn Macdonald, Harrison, NY (US);
Andrew J. Murphy, Croton-on-Hudson, NY (US);
John McWhirter, Greenville, NC (US);
Naxin Tu, Pleasantville, NY (US);
Vera Voronina, North Bethesda, MD (US);
Cagan Gurer, Chappaqua, NY (US);
Karolina Meagher, Yorktown Heights, NY (US);
Sean Stevens, Del Mar, CA (US);
Regeneron Pharmaceuticals, Inc., Tarrytown, NY (US);
Abstract
The invention provides a genetically modified non-human animal that comprises in its genome unrearranged T cell receptor variable gene loci, as well as embryos, cells, and tissues comprising the same. Also provided are constructs for making said genetically modified non-human animal and methods of making the same. Various methods of using the genetically modified non-human animal are also provided.