The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 13, 2022
Filed:
Aug. 21, 2018
Hoffmann-la Roche Inc., Little Falls, NJ (US);
Peter Bruenker, Schlieren, CH;
Frank Herting, Penzberg, DE;
Sylvia Herter, Schlieren, CH;
Christian Klein, Schlieren, CH;
Ekkehard Moessner, Schlieren, CH;
Tilman Schlothauer, Penzberg, DE;
Hoffmann-La Roche Inc., Little Falls, NJ (US);
Abstract
The present invention relates to modified antibodies. In particular, the present invention relates to recombinant monoclonal antibodies having altered ability to induce direct cell death and effector function. In addition, the present invention relates to nucleic acid molecules encoding such antibodies, and vectors and host cells comprising such nucleic acid molecules. The invention further relates to methods for producing the antibodies of the invention, and to methods of using these antibodies in treatment of disease.