The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 13, 2022
Filed:
Apr. 18, 2019
Applicant:
Xencor, Inc., Monrovia, CA (US);
Inventors:
Matthew Bernett, Monrovia, CA (US);
John Desjarlais, Pasadena, CA (US);
Rumana Rashid, Temple City, CA (US);
Rajat Varma, Monrovia, CA (US);
Christine Bonzon, Los Angeles, CA (US);
Assignee:
Xencor, Inc., Monrovia, CA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61K 39/395 (2006.01); C07K 14/715 (2006.01); A61K 38/17 (2006.01); C12N 15/63 (2006.01); A61K 38/20 (2006.01); C07K 14/54 (2006.01);
U.S. Cl.
CPC ...
C07K 14/7155 (2013.01); A61K 38/1793 (2013.01); A61K 38/2086 (2013.01); A61K 39/3955 (2013.01); C07K 14/5443 (2013.01); C12N 15/63 (2013.01); C07K 2319/30 (2013.01);
Abstract
The present invention is directed to novel PD-1-targeted IL-15/Rα-Fc fusion proteins comprising an IL-15/IL-15Rα Fc-fusion protein and a PD-1 antigen binding domain. The PD-1-targeted IL-15/Rα-Fc fusion proteins can be administered to a patient to treat cancer.