The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 13, 2022

Filed:

May. 10, 2019
Applicant:

Alar Pharmaceuticals Inc., Taichung, TW;

Inventors:

Tong-Ho Lin, Taichung, TW;

Yung-Shun Wen, Taichung, TW;

Jui-Wei Liang, Taichung, TW;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 489/04 (2006.01); A61K 9/00 (2006.01); A61K 9/08 (2006.01); A61K 9/50 (2006.01); A61K 47/26 (2006.01); A61K 47/34 (2017.01);
U.S. Cl.
CPC ...
C07D 489/04 (2013.01); A61K 9/0019 (2013.01); A61K 9/08 (2013.01); A61K 9/5031 (2013.01); A61K 47/26 (2013.01); A61K 47/34 (2013.01); C07B 2200/13 (2013.01);
Abstract

This disclosure relates to crystalline forms of 3-acyl-buprenorphine derivatives and sustained release injectable pharmaceutical compositions for treatment of opioid dependence, pain or depression, including an aqueous suspension of crystalline 3-acyl-buprenoprhine, or a pharmaceutically acceptable salt thereof, wherein the composition does not include an organic solvent, a polylactide polymer, a polyglycolide polymer, or a copolymer of polylactide and polyglycolide. This disclosure also includes 3-acyl-buprenoprhine or a pharmaceutically acceptable salt thereof prepared in a controlled release matrix, including poly(lactide-co-glycolide), sucrose acetoisobutyrate, lecithin, diolein and a combination of two or more thereof.


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