The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 13, 2022
Filed:
Jun. 30, 2020
Applicant:
The Regents of the University of California, Oakland, CA (US);
Inventors:
Michael E. Jung, Los Angeles, CA (US);
Jing Huang, Los Angeles, CA (US);
Yanpeng Xing, Los Angeles, CA (US);
Brett E. Lomenick, Los Angeles, CA (US);
Min Chai, Los Angeles, CA (US);
Xudong Fu, Los Angeles, CA (US);
Assignee:
The Regents of the University of California, Oakland, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07D 319/12 (2006.01); C07D 317/34 (2006.01); C07C 69/007 (2006.01); C07F 9/113 (2006.01);
U.S. Cl.
CPC ...
C07D 319/12 (2013.01); C07C 69/007 (2013.01); C07D 317/34 (2013.01); C07F 9/113 (2013.01);
Abstract
The present disclosure provides compounds of Formula (VIA), Formula (IIIA), Formula (IVA), and Formula (VA). The compounds are prodrugs of alpha-ketoglutarate, alpha-ketobutryrate, alpha-ketoisovalerate, and alpha-ketoisohexanoate, which are useful in treating or preventing age related diseases, disorders, or conditions.