The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 13, 2022
Filed:
Oct. 07, 2019
Applicants:
City of Hope, Duarte, CA (US);
The National and Kapodistrian University of Athens, Athens, GR;
Inventors:
Assignees:
City of Hope, Duarte, CA (US);
The National and Kapodistrian University of Athens, Athens, GR;
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 209/40 (2006.01); C07D 401/14 (2006.01);
U.S. Cl.
CPC ...
C07D 209/40 (2013.01); C07D 401/14 (2013.01);
Abstract
Indirubin is the major active anti-tumor component of a traditional Chinese herbal medicine used for treatment of chronic myelogenous leukemia (CML). Indirubin derivatives (IRDs) potently reduce the viabilities of various cancer cells and affect kinase activities. IRDs disclosed herein provide new therapeutics for cancer and conditions regulated by the kinase activities.