The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 13, 2022

Filed:

Nov. 30, 2021
Applicant:

Conduit, Inc., Revere, MA (US);

Inventors:

Logan Thrasher Collins, Revere, MA (US);

Ryan Robinson, Revere, MA (US);

Assignee:

Conduit Inc., Revere, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01L 3/00 (2006.01); G01N 33/53 (2006.01); C12Q 1/6834 (2018.01); C12Q 1/6853 (2018.01);
U.S. Cl.
CPC ...
B01L 3/5027 (2013.01); C12Q 1/6834 (2013.01); C12Q 1/6853 (2013.01); G01N 33/5308 (2013.01); B01L 2300/04 (2013.01); B01L 2300/0861 (2013.01);
Abstract

Provided herein are compositions and devices for diagnosing and treating a viral infection in a subject and/or detecting a viral nucleic acid in a sample. In one example, a sample is treated in a first chamber and the sample is flowed into a second chamber, where any pathogenic nucleic acid is detected by oligonucleotides that are specific to the pathogen under test. Further, the oligonucleotides comprise a cleavage site for a restriction enzyme in the second chamber, which cleaves oligonucleotide-pathogenic nucleic acid hybrid resulting in the exposure of an enzyme that was being held by the oligonucleotide to its substrate, which generates a colorimetric and/or another visual readout.


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