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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11524270 B1

PDFFull Text
Date of Patent:
Dec. 13, 2022

Filed:

Apr. 23, 2019

Method of mixing a pharmaceutical solution and mixing system

Applicants:

Baxter International Inc., Deerfield, IL (US);

Baxter Healthcare SA, Glattpark, CH;

Inventors:

William Spencer Hurst, Burlington, WI (US);

Kent Alan Williams, Chicago, IL (US);

Donald A. Smith, Trevor, WI (US);

Michael P. Wehrli, Cary, IL (US);

Luis Ernesto Criales Escobar, Grayslake, IL (US);

Jessica Tam, Chicago, IL (US);

Joseph Edward Bigalke, Spring Grove, IL (US);

Gert Najdeni, Winnetka, IL (US);

Karan Kerwell, Deerfield, IL (US);

Lushan Zhou, Ingleside, IL (US);

Michael Imeobong Essien, Chicago, IL (US);

Assignees:

BAXTER INTERNATIONAL INC., Deerfield, IL (US);

BAXTER HEALTHCARE SA, Glattpark, CH;

Attorney:

Marshall, Gerstein & Borun LLP

Primary Examiner:

David L Sorkin

Int. Cl.
CPC ...
B01F 33/40 (2022.01); B01F 35/513 (2022.01); A61J 1/10 (2006.01); A61J 1/20 (2006.01); B01F 21/20 (2022.01); B01F 21/00 (2022.01); B01F 35/00 (2022.01); B01F 35/71 (2022.01); B01F 101/22 (2022.01);
U.S. Cl.
CPC ...
B01F 33/406 (2022.01); A61J 1/10 (2013.01); A61J 1/2003 (2015.05); A61J 1/2037 (2015.05); A61J 1/2082 (2015.05); B01F 21/20 (2022.01); B01F 21/30 (2022.01); B01F 33/401 (2022.01); B01F 35/187 (2022.01); B01F 35/513 (2022.01); B01F 35/7176 (2022.01); B01F 2101/22 (2022.01);
Abstract

A method of mixing a pharmaceutical solution including adding a gas into an interior compartment of a mix bag to form a headspace. The interior compartment of the mix bag includes a top portion and a bottom portion. The headspace adjacent to the top portion contains gas. The method includes adding a solvent into the mix bag, and establishing a bubble column in the interior compartment by activating a recirculation assembly. The recirculation assembly includes a connecting pathway operably coupled to a recirculation pump. A first end of the connecting pathway is coupled to a top gas recirculation port and a second end is coupled to a bottom gas recirculation port of the mix bag such that the recirculation pump draws the gas from the headspace and delivers the gas to the interior compartment via the bottom gas recirculation port. The method includes adding a solute into the mix bag.

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