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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11524092 B1

PDFFull Text
Date of Patent:
Dec. 13, 2022

Filed:

Oct. 04, 2018

Particle suitable for the manufacture of an implantable soft tissue engineering material

Applicant:

École Polytechnique Fédérale DE Lausanne (Epfl), Lausanne, CH;

Inventors:

Amélie Béduer, Lausanne, CH;

Thomas Braschler, Chavannes, CH;

Philippe Renaud, Préverenges, CH;

Assignee:

Ecole Polytechnique Federale de Lausanne (EPFL), Lausanne, CH;

Attorney:

Pabst Patent Group LLP

Primary Examiner:

Casey S Hagopian

Int. Cl.
CPC ...
A61L 27/20 (2006.01); A61F 2/00 (2006.01); A61L 27/16 (2006.01); A61L 27/18 (2006.01); A61L 27/24 (2006.01); A61L 27/52 (2006.01); A61L 27/54 (2006.01); A61L 27/36 (2006.01); A61L 27/56 (2006.01); A61F 2/12 (2006.01); A61L 24/00 (2006.01); A61K 9/14 (2006.01);
U.S. Cl.
CPC ...
A61L 27/20 (2013.01); A61F 2/0059 (2013.01); A61F 2/12 (2013.01); A61K 9/141 (2013.01); A61L 24/0036 (2013.01); A61L 27/16 (2013.01); A61L 27/18 (2013.01); A61L 27/24 (2013.01); A61L 27/3633 (2013.01); A61L 27/52 (2013.01); A61L 27/54 (2013.01); A61F 2240/001 (2013.01); A61L 27/56 (2013.01); A61L 2300/00 (2013.01); A61L 2300/23 (2013.01); A61L 2400/06 (2013.01); A61L 2430/04 (2013.01); A61L 2430/34 (2013.01);
Abstract

The particle () is suitable for the manufacture of an implantable soft tissue engineering material and comprises: a three-dimensionally warped and branched sheet () where (i) the three-dimensionally warped and branched sheet () is made from a biocompatible material having a Young's modulus of 1 kPa to 1 GPa; (ii) the three-dimensionally warped and branched sheet () has an irregular shape which is encompassed in a virtual three-dimensional envelope () having a volume V; (iii) the three-dimensionally warped and branched sheet () has a mean sheet thickness T; iv) the three-dimensionally warped and branched sheet () has a volume V; (v) the particle () has a Young's modulus of 100 Pa to 15 kPa; and (vi) the particle () further comprises a number of protrusions where the three-dimensionally warped and branched sheet () reaches the envelope (); (vii) the particle () has a number of interconnected channel-type conduits () defined by the branching of the sheet () and/or by voids in the sheet (); and (viii) where the conduits () have (a) a mean diameter D; and (b) an anisotropicity index of 1.01 to 5.00.

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