The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 13, 2022
Filed:
Feb. 04, 2021
University of Georgia Research Foundation, Inc., Athens, GA (US);
The Ohio State University, Columbus, OH (US);
Ramesh Kumar Selvaraj, Bogart, GA (US);
Gabriel Akerele, Athens, GA (US);
Sankar Renu, Wooster, OH (US);
Renukaradhya J. Gourapura, Wooster, OH (US);
UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC, Athens, GA (US);
THE OHIO STATE UNIVERSITY, Columbus, OH (US);
Abstract
The present disclosure relates to nanoparticle compositions for use as vaccines againstin poultry which causes necrotic enteritis in poultry. Such compositions include one or moreextracellular proteins entrapped in a polyanhydride or chitosan nanoparticle. The one or moreextracellular proteins may include one or moretoxins, such as, for example, alpha toxin (CPA), beta toxin (CPB), epsilon toxin (ETX), iota toxin (ITX), perfringolysin O (PFO), enterotoxin (CPE), beta2 toxin (CPB2), or NetB toxin. In some aspects, the composition further includes aflagellar protein. The present invention also includes methods for the oral delivery of one or moreextracellular proteins to the mucosal membrane of the intestinal tract of a bird of the order Galliformes.