The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 13, 2022

Filed:

Apr. 22, 2019
Applicant:

Contrafect Corporation, Yonkers, NY (US);

Inventors:

Raymond Schuch, Mountain Lakes, NJ (US);

Robert C. Nowinski, New York, NY (US);

Michael Wittekind, Bainbridge Island, WA (US);

Babar Khan, Kingston, NY (US);

Jimmy Rotolo, New York, NY (US);

Assignee:

CONTRAFECT CORPORATION, Yonkers, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/16 (2006.01); C12N 9/50 (2006.01); A01N 63/50 (2020.01); A61L 29/08 (2006.01); A61L 29/16 (2006.01); C07K 14/315 (2006.01); A61K 38/47 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 38/16 (2013.01); A01N 63/50 (2020.01); A61K 38/164 (2013.01); A61K 38/47 (2013.01); A61K 45/06 (2013.01); A61L 29/08 (2013.01); A61L 29/16 (2013.01); C07K 14/315 (2013.01); C12N 9/503 (2013.01); C12Y 302/01017 (2013.01); A61L 2300/404 (2013.01); A61L 2300/406 (2013.01); A61L 2420/00 (2013.01);
Abstract

The present invention provides methods for the prevention, control, disruption and treatment of bacterial biofilms with lysin, particularly lysin having capability to kill Staphlococcal bacteria, including drug resistant, particularly the lysin PlySs2. The invention also provides compositions and methods for use in treatment or modulation of bacterial biofilm(s) and biofilm formation.


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