The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 13, 2022
Filed:
Nov. 13, 2018
Jiangsu Kanion Pharmaceutical Co., Ltd., Jiangsu, CN;
Wei Xiao, Jiangsu, CN;
Enli Zhou, Jiangsu, CN;
Zeyu Cao, Jiangsu, CN;
Xiujuan Chang, Jiangsu, CN;
Xiaodong Kang, Jiangsu, CN;
Yongxiang Wang, Jiangsu, CN;
Hanfei Hu, Jiangsu, CN;
Yun Wu, Jiangsu, CN;
Zhenzhong Wang, Jiangsu, CN;
Chenfeng Zhang, Jiangsu, CN;
JIANGSU KANION PHARMACEUTICAL CO., LTD, Jiangsu, CN;
Abstract
Aditerpene lactone composition is provided. The composition has the effect of improving a depressive state. The composition can prolong a tail flick interval time and a swimming interval time of a mouse to different degrees and can also increase the frequency of escaping from electric shock to different degrees. The additional addition of a certain amount of ginkgolide C, ginkgolide J, and ginkgolide L greatly enhances the effect of improving the depressive state. It is further proved through experiments that after the provision of thediterpene lactone composition, indexes, such as SOD, MDA, GSH, and TAC, can be improved to different degrees. For example, after the addition of a certain amount of ginkgolide C, ginkgolide J, and ginkgolide L, the improving effect gets more obvious, the oxidative stress level can be better improved, and the oxidative damage can be relieved.