The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 13, 2022
Filed:
Nov. 03, 2016
Applicant:
Beijing Normal University Hong Kong Baptist University United International College, Guangdong, CN;
Inventors:
Stephen Chung, Hong Kong, CN;
Shiqing Zhang, Guangdong, CN;
Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/69 (2006.01); A61K 38/05 (2006.01); A61K 38/06 (2006.01); A61K 31/11 (2006.01); A61K 31/121 (2006.01); A61K 31/191 (2006.01); A61K 31/198 (2006.01); A61K 31/4188 (2006.01); A61K 31/4402 (2006.01); A61K 31/57 (2006.01); A61K 31/7004 (2006.01); A61K 45/06 (2006.01); A61K 31/19 (2006.01); A61P 35/00 (2006.01); A61K 38/55 (2006.01);
U.S. Cl.
CPC ...
A61K 31/69 (2013.01); A61K 31/11 (2013.01); A61K 31/121 (2013.01); A61K 31/19 (2013.01); A61K 31/191 (2013.01); A61K 31/198 (2013.01); A61K 31/4188 (2013.01); A61K 31/4402 (2013.01); A61K 31/57 (2013.01); A61K 31/7004 (2013.01); A61K 38/05 (2013.01); A61K 38/06 (2013.01); A61K 38/55 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01);
Abstract
The present disclosure relates to, inter alia, a method of treating cancer in a human patient in need thereof, comprising administering a therapeutically effective amount of a substrate of AKR1B1, AKR1B10, or both to said patient, wherein said patient has, or is suspected to have, cancer cells with elevated levels of AKR1B1, AKR1B10, or both, wherein said substrate is not 2-deoxy-D-glucose.