The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 06, 2022

Filed:

Apr. 05, 2021
Applicants:

Case Western Reserve University, Cleveland, OH (US);

Government of the United States, As Represented BY the Secretary of Commerce, Gaithersburg, MD (US);

The Regents of the University of Colorado, a Body Corporate, Denver, CO (US);

Inventors:

Kathryn Keenan, Boulder, CO (US);

Megan Poorman, Boulder, CO (US);

Rasim Boyacioglu, Cleveland Heights, OH (US);

Mark A. Griswold, Shaker Heights, OH (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01R 33/50 (2006.01); G01R 33/56 (2006.01); A61B 5/055 (2006.01); A61B 5/00 (2006.01); G01R 33/385 (2006.01);
U.S. Cl.
CPC ...
G01R 33/50 (2013.01); A61B 5/0037 (2013.01); A61B 5/055 (2013.01); G01R 33/385 (2013.01); G01R 33/5608 (2013.01);
Abstract

A method for temperature quantification using magnetic resonance fingerprinting (MRF) includes acquiring MRF data from a region of interest in a subject using an MRF pulse sequence with smoothly varying RF phase for MR resonant frequencies that is played out continuously. For each of a plurality of time intervals during acquisition of the MRF data the method further includes comparing a set of the MRF data associated with the time interval to an MRF dictionary to determine at least one quantitative parameter of the acquired MRF data, determining a temperature change based on the at least one quantitative parameter and generating a quantitative map of the temperature change in the region of interest. The region of interest can include aqueous and adipose tissue.


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