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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11519004 B1

PDFFull Text
Date of Patent:
Dec. 06, 2022

Filed:

Mar. 19, 2019

Transcription modulation in animals using crispr/cas systems

Applicant:

Regeneron Pharmaceuticals, Inc., Tarrytown, NY (US);

Inventors:

Charleen Hunt, Dumont, NJ (US);

Suzanne Hartford, Putnam Valley, NY (US);

Guochun Gong, Pleasantville, NY (US);

Brian Zambrowicz, Sleepy Hollow, NY (US);

Assignee:

Regeneran Pharmaceuticals, Inc., Tarrytown, NY (US);

Attorneys:

Yongjin Choi

Alston & Bird LLP

Primary Examiner:

Arthur S Leonard

Int. Cl.
CPC ...
C12N 15/85 (2006.01); C12N 15/86 (2006.01); C12N 15/90 (2006.01); C12N 15/113 (2010.01); C12N 9/22 (2006.01); A01K 67/027 (2006.01);
U.S. Cl.
CPC ...
C12N 15/8509 (2013.01); A01K 67/0275 (2013.01); C12N 9/22 (2013.01); C12N 15/113 (2013.01); C12N 15/86 (2013.01); C12N 15/907 (2013.01); A01K 2217/07 (2013.01); A01K 2217/072 (2013.01); A01K 2217/206 (2013.01); A01K 2227/105 (2013.01); A01K 2267/03 (2013.01); A01K 2267/0306 (2013.01); A01K 2267/0362 (2013.01); C12N 2015/8527 (2013.01); C12N 2310/20 (2017.05); C12N 2310/531 (2013.01); C12N 2320/11 (2013.01); C12N 2750/14143 (2013.01); C12N 2800/30 (2013.01); C12N 2830/008 (2013.01);
Abstract

Non-human animal cells and non-human animals comprising CRISPR/Cas synergistic activation mediator system components and methods of making and using such non-human animal cells and non-human animals are provided. Methods are provided for using such non-human animals to increase expression of target genes in vivo and to assess CRISPR/Cas synergistic activation mediator systems for the ability to increase expression of target genes in vivo.

Find Patent Forward Citations

Hunt, Charleen. (2022). Transcription modulation in animals using crispr/cas systems (U.S. Patent No. 11519004). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11519004

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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