The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 06, 2022

Filed:

Aug. 29, 2019
Applicant:

Hcw Biologies, Inc., Miramar, FL (US);

Inventor:

Hing Wong, Miramar, FL (US);

Assignee:

HCW Biologics, Inc., Miramar, FL (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 14/54 (2006.01); C07K 14/71 (2006.01); C07K 14/715 (2006.01); C07K 14/745 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
C07K 14/5434 (2013.01); C07K 14/54 (2013.01); C07K 14/5418 (2013.01); C07K 14/71 (2013.01); C07K 14/7155 (2013.01); C07K 14/745 (2013.01); C07K 16/283 (2013.01); C07K 2317/622 (2013.01); C07K 2319/02 (2013.01); C07K 2319/03 (2013.01); C07K 2319/30 (2013.01);
Abstract

Provided herein are multi-chain chimeric polypeptides that include: (a) a first chimeric polypeptide including a first target-binding domain, a soluble tissue factor domain, and a first domain of a pair of affinity domains; and (b) a second chimeric polypeptide including a second domain of a pair of affinity domains and a second target-binding domain, where the first chimeric polypeptide and the second chimeric polypeptide associate through the binding of the first domain and the second domain of the pair of affinity domains. Also provided here are methods of using these multi-chain chimeric polypeptides and nucleic acids encoding these multi-chain chimeric polypeptides.


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