The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 06, 2022

Filed:

Jul. 09, 2019
Applicants:

Victoria Link Limited, Wellington, NZ;

Albert Einstein College of Medicine, Bronx, NY (US);

Timothy Dravitzki, Porirua, NZ;

Inventors:

Peter Charles Tyler, Wellington, NZ;

Farah Lamiable-Oulaidi, Lower Hutt, NZ;

Anthony David Woolhouse, Porirua, NZ;

Shivali Ashwin Gulab, New York, NY (US);

Karl Jürgen Shaffer, Lower Hutt, NZ;

Ashna Ashneen Khan, Auckland, NZ;

Douglas Ronald Crump, Wellington, NZ;

Vern L. Schramm, New Rochelle, NY (US);

Quan Du, San Diego, CA (US);

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 19/16 (2006.01);
U.S. Cl.
CPC ...
C07H 19/16 (2013.01);
Abstract

Provided herein are inhibitors of DNA methyltransferase 1 (an enzyme responsible for the maintenance of DNA CpG methylation marks in human cells) and their use for inhibiting DNA methyltransferase 1. The invention relates to compounds, pharmaceutical compositions, and methods for inhibiting DNA methyltransferase 1. The inhibitors are compounds of the general formula:


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