The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 06, 2022

Filed:

Sep. 18, 2020
Applicant:

Nikang Therapeutics, Inc., Wilmington, DE (US);

Inventors:

Jiping Fu, Danville, CA (US);

Yan Lou, Pleasanton, CA (US);

Yigang He, Newark, DE (US);

Assignee:

NIKANG THERAPEUTICS, INC., Wilmington, DE (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 519/00 (2006.01); A61P 35/00 (2006.01); A61K 31/5383 (2006.01); C07D 401/14 (2006.01); C07D 471/10 (2006.01); C07D 491/107 (2006.01);
U.S. Cl.
CPC ...
C07D 519/00 (2013.01); A61K 31/5383 (2013.01); A61P 35/00 (2018.01); C07D 401/14 (2013.01); C07D 471/10 (2013.01); C07D 491/107 (2013.01);
Abstract

The present disclosure provides certain fused tricyclic ring derivatives that are Src Homology-2 phosphatase (SHP2) inhibitors and are therefore useful for the treatment of diseases treatable by inhibition of SHP2. Also provided are pharmaceutical compositions containing such compounds and processes for preparing such compounds.


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