The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 06, 2022
Filed:
Dec. 04, 2019
Scohia Pharma, Inc., Kanagawa, JP;
Shigemitsu Matsumoto, Kanagawa, JP;
Ryoma Hara, Kanagawa, JP;
Naoyoshi Noguchi, Kanagawa, JP;
Hideto Fukushi, Kanagawa, JP;
Ayumu Niida, Kanagawa, JP;
Satoshi Sasaki, Kanagawa, JP;
Minoru Ikoma, Kanagawa, JP;
Toshitake Kobayashi, Kanagawa, JP;
Tsuyoshi Maekawa, Kanagawa, JP;
SCOHIA PHARMA, INC., Kanagawa, JP;
Abstract
A compound represented by the following formula (I): wherein each symbol in the formula is as described herein or a salt thereof has an NRF2 activating activity, and is expected to be useful as a preventive or therapeutic agent for diseases associated with oxidative stress, in particular, hepatic disease (for example, non-alcoholic steatohepatitis (NASH)), cardiovascular disease (for example, heart failure or pulmonary arterial hypertension), lung disease (for example, chronic obstructive pulmonary disease (COPD)), kidney disease (for example, chronic kidney disease (CKD) or acute kidney injury (AKI)), central nervous system disease (for example, Parkinson's disease), mitochondrial disease (for example, Friedreich motor ataxia, mitochondrial myopathy), inflammatory disease (for example, multiple sclerosis (MS), inflammatory bowel disease (IBD)), sickle cell disease, cancer, or the like.