The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 06, 2022

Filed:

Nov. 27, 2018
Applicant:

Children's Medical Center Corporation, Boston, MA (US);

Inventors:

Richard Mulligan, Cambridge, MA (US);

George J. Murphy, Boston, MA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/85 (2006.01); A61K 48/00 (2006.01); C12Q 1/6813 (2018.01); C12N 15/86 (2006.01); A61K 31/7036 (2006.01); A61K 35/12 (2015.01);
U.S. Cl.
CPC ...
A61K 48/0066 (2013.01); A61K 31/7036 (2013.01); A61K 35/12 (2013.01); C12N 15/85 (2013.01); C12N 15/86 (2013.01); C12Q 1/6813 (2013.01);
Abstract

In certain embodiments, the disclosure relates to compositions and methods relating to a translation-based gene regulation system that functions in mammalian cells. In certain specific embodiments, the disclosure relates to methods of regulating gene expression via modulating translation termination.


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