The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 06, 2022
Filed:
May. 30, 2019
University of Pittsburgh—of the Commonwealth System of Higher Education, Pittsburgh, PA (US);
Jianhua Luo, Wexford, PA (US);
Zhanghui Chen, Huzhou, CN;
Yanping Yu, Wexford, PA (US);
George Michalopoulos, Pittsburgh, PA (US);
Joel B. Nelson, Pittsburgh, PA (US);
Chien-Cheng Tseng, Pittsburgh, PA (US);
University of Pittsburgh—of the Commonwealth System of Higher Education, Pittsburgh, PA (US);
Abstract
The present invention relates to methods for treating patients having cancer or a premalignant or neoplastic condition. It is based, at least in part, on the discovery that a genome editing technique that specifically targets a fusion gene can induce cell death in a cancer cell other than a prostate cancer cell, e.g., a hepatocellular cancer cell, having the fusion gene. The present invention provides methods for treating cancer patients that include performing a genome editing technique targeting a fusion gene present within one or more cells of a subject to produce an anti-cancer effect.