The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 06, 2022
Filed:
Dec. 31, 2019
Applicant:
Bayer Aktiengesellschaft, Leverkusen, DE;
Inventors:
Sabine Hoff, Potsdam, DE;
Lars Rose, Berlin, DE;
Dieter Zopf, Berlin, DE;
Fabian Kiessling, Aachen, DE;
Wiltrud Lederle, Aachen, DE;
Dennis Doleschel, Aachen, DE;
Assignee:
BAYER HEALTHCARE LLC, Whippany, NJ (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); A61P 35/00 (2006.01); A61K 9/00 (2006.01); A61K 31/44 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/3955 (2013.01); A61K 9/0019 (2013.01); A61K 31/44 (2013.01); A61P 35/00 (2018.01); A61K 2039/505 (2013.01);
Abstract
The present invention relates to pharmaceutical compositions and combinations comprising regorafenib or its hydrate, solvate, metabolite or pharmaceutically acceptable salt or a polymorph thereof and a PD-1/PD-L1(2) inhibitor for treating, preventing or managing diseases and conditions including hyperproliferative disorders such as cancer in humans and other mammals.