The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 06, 2022

Filed:

Jan. 11, 2016
Applicant:

The Board of Trustees of the University of Illinois, Urbana, IL (US);

Inventors:

Martin D. Burke, Champaign, IL (US);

Anthony S. Grillo, Champaign, IL (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/122 (2006.01); A61P 7/06 (2006.01); A61P 39/04 (2006.01); G01N 33/50 (2006.01); A61K 45/06 (2006.01); A61K 9/00 (2006.01); A61K 31/34 (2006.01); A61K 31/351 (2006.01); A61K 31/4184 (2006.01); A61K 31/4412 (2006.01); A61K 31/7048 (2006.01);
U.S. Cl.
CPC ...
A61K 31/122 (2013.01); A61K 9/0019 (2013.01); A61K 9/0053 (2013.01); A61K 31/34 (2013.01); A61K 31/351 (2013.01); A61K 31/4184 (2013.01); A61K 31/4412 (2013.01); A61K 31/7048 (2013.01); A61K 45/06 (2013.01); A61P 7/06 (2018.01); A61P 39/04 (2018.01); G01N 33/5008 (2013.01); G01N 2800/22 (2013.01);
Abstract

Provided are methods of treating a disease or condition characterized by a deficiency of or a defect in an iron transporter using a small molecule. For example, the method may increase transepithelial iron transport, or it may increase iron release. Additionally, the small molecule may be hinokitiol, or it may be selected from the group consisting of amphotericin B, calcimycin, nonactin, deferiprone, purpurogallin, and maltol. Also provided is a method of identifying a compound capable of treating a disease or condition characterized by a deficiency of or a defect in an iron transporter.


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