The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 29, 2022

Filed:

Mar. 19, 2018
Applicant:

International Business Machines Corporation, Armonk, NY (US);

Inventors:

Govind Kaigala, Rueschlikon, CH;

Anna Fomitcheva Khartchenko, Zurich, CH;

Aditya Kashyap, Zurich, CH;

Maria Gabrani, Thalwil, CH;

Pushpak Pati, Zurich, CH;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G16B 40/00 (2019.01); G16H 50/30 (2018.01); G06V 20/69 (2022.01);
U.S. Cl.
CPC ...
G16B 40/00 (2019.02); G06V 20/698 (2022.01); G16H 50/30 (2018.01); G01N 2800/50 (2013.01); G01N 2800/60 (2013.01); G06T 2207/30004 (2013.01);
Abstract

Embodiments of the invention relate to a computer-implemented method for quantifying a biomarker in a tissue sample of an organism. An image analysis system receives images of a stained tissue sample. Each received digital image depicts the tissue sample region at the end of an exposure interval. The system analyzes the intensity values and exposure intervals of the received digital images for determining the time when the intensity values corresponding to the plurality of exposure intervals ordered according to ascending exposure interval lengths reach a plateau (saturation residence time—SRT). The system determines the amount of a biomarker in the tissue sample and/or predicts a tumor stage and/or a treatment recommendation as a function of the SRT.


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