The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 29, 2022

Filed:

Dec. 02, 2015
Applicant:

Eiken Kagaku Kabushiki Kaisha, Tokyo, JP;

Inventor:

Satoru Michiyuki, Tochigi, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); C07H 21/00 (2006.01); G01N 33/00 (2006.01); C12Q 1/6827 (2018.01); C12N 15/09 (2006.01); C12Q 1/68 (2018.01); C12Q 1/6825 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/6827 (2013.01); C12N 15/09 (2013.01); C12Q 1/68 (2013.01); C12Q 1/6825 (2013.01);
Abstract

The present invention provides an oligonucleotide probe for single nucleotide polymorphism detection to be used for a target nucleic acid where a single nucleotide polymorphism is present, the oligonucleotide probe comprising a reporter region, an anchor region, and a linker region. The reporter region comprises: an oligonucleotide consisting of a sequence perfectly matching when a nucleotide of the single nucleotide polymorphism is a first nucleotide, and mismatching when the nucleotide of the single nucleotide polymorphism is a nucleotide other than the first nucleotide; and a fluorescent dye quenching when the reporter region hybridize to the target nucleic acid.


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