The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 29, 2022

Filed:

Jan. 12, 2021
Applicant:

Fluent Biosciences Inc., Watertown, MA (US);

Inventors:

Kristina Fontanez, Arlington, MA (US);

Robert Meltzer, Belmont, MA (US);

Yi Xue, Shrewsbury, MA (US);

Sepehr Kiani, Watertown, MA (US);

Assignee:

FLUENT BIOSCIENCES INC., Watertown, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2018.01); C12Q 1/02 (2006.01); C12Q 1/6869 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/025 (2013.01); C12Q 1/6869 (2013.01);
Abstract

The invention provides methods and systems for drug screening by segregating single cells into droplets simultaneously and providing candidate compound to the single cells to measure cellular response. Methods of the present invention combine template particles with a plurality of single cells in a tube, generate in the tube monodispersed droplets simultaneously that encapsulate a single one of the template particles and single one of the single cells, provide to the single cells one or more candidate compounds, and measure a cellular response to the one or more candidate compounds.


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