The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 29, 2022

Filed:

Nov. 30, 2017
Applicant:

Beijing Kansenbio Technology Ltd., Beijing, CN;

Inventors:

Zhen Chen, Beijing, CN;

Dehua Liu, Beijing, CN;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12P 17/12 (2006.01); C12N 15/77 (2006.01); C12N 1/20 (2006.01); C12R 1/15 (2006.01);
U.S. Cl.
CPC ...
C12P 17/12 (2013.01); C12N 15/77 (2013.01); C12N 1/205 (2021.05); C12R 2001/15 (2021.05); C12Y 207/02004 (2013.01); C12Y 403/03007 (2015.07);
Abstract

A method for producing ectoine by fermenting recombinant. The recombinantis obtained by overexpressing, in, an aspartokinase gene lysC of which feedback inhibition is relieved, then replacing the promoter of the dihydrodipicolinate synthase in the recombinant bacterium to attenuate the activity of the dihydropyrimidine dicarboxylic acid synthase, and then transforming the recombinant bacterium with the ectoine synthetic path related gene ectABC. The recombinantcan be fermented using different cheap raw materials under a low salt condition to produce ectoine, and use cheap corn slurry instead of expensive yeast powder as a nutritional component, so as to further reduce the costs of the raw materials. In addition, the recombinantsolves the biosafety problem, simplifies the post-extraction process, and has a good market application prospect.


Find Patent Forward Citations

Loading…